Enantiomer Separation of Miconazole by Capillary Electrophoresis with Dual Cyclodextrin Systems
نویسندگان
چکیده
منابع مشابه
Enantiomer separation of miconazole by capillary electrophoresis with dual cyclodextrin systems.
A cyclodextrin-modified micellar capillary electrophoretic method (MECC) was developed using mixtures of beta, cyclodextrins (beta-CD) and mono-3-O-phenylcarbamoyl-beta-CD as chiral additives for the chiral separation of miconazole with the dual CDs systems. The enantiomers were resolved using a running buffer of 50 mmol/L borate pH 9.5 containing 15 mmol/L beta-CD and 15 mmol/L mono-3-O-phenyl...
متن کاملMethod development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.
Capillary electrophoresis (CE) has become a powerful tool for enantiomer separations during the last decade. Since 1993, the author has investigated enantiomer separations by affinity capillary electrophoresis (affinity CE) with some proteins and by cyclodextrin electrokinetic chromatography (CDEKC) with some charged cyclodextrins (CDs). Many successful enantiomer separations are demonstrated f...
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Enantiomer separation of mandelates and their analogs, which are important intermediates in asymmetric synthetic and pharmaceutical chemistry, was investigated by capillary gas chromatography using different cyclodextrin derivative chiral stationary phases (CD CSPs). The used cyclodextrin derivatives included permethylated beta-CD (PMBCD), permethylated gamma-CD, heptakis(2,6-di-O-butyl-3-O-but...
متن کاملChiral separation of several drugs using electrophoresis with dual cyclodextrin systems.
represent high separation efficiencies, rapid analysis time, and low reagent consumption, they have been widely studied as promising analytical methodologies.1–4 Chiral separation is one of the major objectives in CE as well as in chromatographic methods. In these separations, a diverse range of CDs (cyclodextrins) have been employed as chiral additives including nonderivative CDs, derivative n...
متن کاملSimultaneous Separation of Eight Lignans in Forsythia suspensa by β-Cyclodextrin-Modified Capillary Zone Electrophoresis.
The aim of the study was to develop an alternative capillary zone electrophoresis (CZE) for simultaneous determination of phillyrin (1), phillygenin (2), epipinoresinol-4-O-β-glucoside (3), pinoresinol-4-O-β-glucoside (4), lariciresinol (5), pinoresinol (6), isolariciresinol (7) and vladinol D (8) in Forsythia suspensa. The structural types of lignans 1-8 could be attributed to bisepoxylignans ...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 2003
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.19.1509